5-Aminolevulinic acid: A matter of life and caveats
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15 صفحه اول5-Aminolevulinic acid synthesis in Escherichia coli.
A hemA mutant of Escherichia coli containing a multicopy plasmid which complemented the mutation excreted 5-aminolevulinic acid (ALA) into the medium. [1-14C]glutamate was substantially incorporated into ALA by this strain, whereas [2-14C]glycine was not. Periodate degradation of labeled ALA showed that C-5 of ALA was derived from C-1 of glutamate. The synthesis of ALA by two sonicate fractions...
متن کاملEffect of Silver Nanoparticles on Improving the Efficacy of 5-Aminolevulinic Acid-Induced Photodynamic Therapy
Introduction: The most important limitation of 5-aminolevulinic acid (5-ALA)-induced photodynamic therapy (PDT) is the efficacy of the cells in converting 5-ALA to protoporphyrin IX. The present study aimed to investigate the effectiveness of silver nanoparticles (AgNPs) with the photosensitivity at the surface plasmon resonance wavelength on 5-ALA-mediated PDT. Material and Methods: First of a...
متن کاملPain associated with photodynamic therapy using 5-aminolevulinic acid or 5-aminolevulinic acid methylester on tape-stripped normal skin.
BACKGROUND Pain during and after topical photodynamic therapy (PDT) is one of the few severe adverse effects of the new treatment of skin diseases. OBJECTIVE To compare the pain experienced in normal skin treated with 5-aminolevulinic acid (ALA) PDT and 5-aminolevulinic methylester (ALA-ME) PDT. DESIGN Double-blind randomized trial. INTERVENTIONS Twenty healthy volunteers were treated ran...
متن کامل5-aminolevulinic acid from photosynthetic bacteria and its applications
Tangprasittipap, A. and Prasertsan, P. 5-aminolevulinic acid from photosynthetic bacteria and its applications Songklanakarin J. Sci. Technol., 2002, 24(4) : 717-725 This paper gives an overview on ALA production by photosynthetic bacteria concerning biosynthesis and regulation as well as its application as herbicide, insecticide and growth stimulator. Recent medical applications in the field o...
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ژورنال
عنوان ژورنال: Journal of Photochemistry and Photobiology
سال: 2021
ISSN: 2666-4690
DOI: 10.1016/j.jpap.2021.100036